Viagra Sublingual: Rapid-Acting Erectile Dysfunction Treatment
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Synonyms | |||
Similar products
Viagra Sublingual represents a significant advancement in the pharmacological management of erectile dysfunction (ED), offering a unique sublingual administration route for the active ingredient sildenafil citrate. This formulation is designed to be placed under the tongue, where it dissolves and is absorbed directly into the bloodstream through the sublingual mucosa. This bypasses first-pass hepatic metabolism, potentially leading to a faster onset of action compared to traditional oral tablets. It is indicated for men experiencing difficulty achieving or maintaining an erection sufficient for satisfactory sexual performance. This product card provides a comprehensive, expert-level overview of its clinical profile for healthcare professionals and informed patients.
Features
- Active Ingredient: Sildenafil Citrate
- Administration Route: Sublingual (placed under the tongue)
- Mechanism of Action: Phosphodiesterase type 5 (PDE5) inhibitor
- Formulation: Fast-dissolving tablet or film
- Onset of Action: Typically within 15-30 minutes post-administration
- Duration of Effect: Up to 4-6 hours, depending on individual patient factors
- Available Strengths: Commonly available in 25 mg, 50 mg, and 100 mg dosage forms
Benefits
- Expedited Therapeutic Onset: The sublingual delivery system facilitates rapid absorption, potentially reducing the waiting time between dosing and the ability to engage in sexual activity compared to standard oral tablets.
- Enhanced Bioavailability: By circumventing the gastrointestinal tract and first-pass liver metabolism, sublingual administration may improve the bioavailability of sildenafil, meaning a lower dose may achieve the desired therapeutic effect.
- Administrative Convenience: The discreet, non-invasive, and waterless administration is advantageous for patients who may have difficulty swallowing conventional pills or who desire more discretion.
- Predictable Pharmacodynamic Profile: Offers a reliable duration of effect, providing a sufficient window for spontaneous sexual activity.
- Proven Efficacy: Leverages the well-established and highly efficacious mechanism of sildenafil citrate, a first-line therapy for ED with a robust clinical history.
Common use
Viagra Sublingual is primarily prescribed for the treatment of erectile dysfunction (ED) in adult men. ED is characterized by the consistent or recurrent inability to attain and/or maintain a penile erection sufficient for satisfactory sexual performance. The medication is used on an as-needed basis prior to anticipated sexual activity. It is crucial to understand that this is a treatment for ED and not a cure; it requires sexual stimulation to be effective. It does not increase sexual desire (libido) and does not offer protection against sexually transmitted diseases.
Dosage and direction
The recommended starting dose for most patients is 50 mg taken approximately 15-30 minutes before sexual activity. Based on efficacy and tolerability, the dose may be increased to a maximum recommended dose of 100 mg or decreased to 25 mg. The dosing range is 25 mg to 100 mg, taken not more than once per day.
Directions for Use:
- Immediately prior to use, tear open the blister pack or pouch.
- With dry hands, place the tablet or film under the tongue.
- Do not chew, swallow, or crush the medication.
- Allow it to dissolve completely. Do not eat or drink anything during the dissolution process.
- The medication will work only in the presence of sexual stimulation.
Precautions
- A comprehensive medical and cardiovascular assessment is recommended prior to initiating any treatment for ED to ensure the patient is healthy enough for sexual activity.
- Use with caution in patients with anatomical deformation of the penis (e.g., angulation, cavernosal fibrosis, Peyronie’s disease), or in conditions that may predispose them to priapism (e.g., sickle cell anemia, multiple myeloma, leukemia).
- Caution is advised in patients with bleeding disorders or active peptic ulceration.
- Non-arteritic anterior ischemic optic neuropathy (NAION) has been reported post-marketing in association with PDE5 inhibitor use. Patients should be advised to seek immediate medical attention in the event of sudden vision loss in one or both eyes.
- Sudden decrease or loss of hearing has been reported. Patients should discontinue use and seek prompt medical attention if such symptoms occur.
- This medication contains sildenafil and should not be used by women or children.
Contraindications
- Concomitant use of any form of organic nitrates (e.g., nitroglycerin, isosorbide mononitrate or dinitrate) or nitric oxide donors in any form. This combination can cause a severe, life-threatening drop in blood pressure.
- Concomitant use with guanylate cyclase stimulators such as riociguat.
- Known hypersensitivity to sildenafil citrate or any other component of the formulation.
- Patients for whom sexual activity is inadvisable due to underlying cardiovascular status.
Possible side effect
Like all medications, Viagra Sublingual can cause side effects, although not everybody gets them. Most are mild to moderate and transient.
Very Common (≥1/10):
- Headache
- Flushing
Common (≥1/100 to <1/10):
- Dyspepsia (indigestion)
- Nasal congestion
- Dizziness
- Visual disturbances (e.g., blurred vision, color tinge, increased light sensitivity)
Uncommon (≥1/1,000 to <1/100):
- Back pain
- Myalgia (muscle pain)
- Nausea
- Rash
Rare (≥1/10,000 to <1/1,000):
- Priapism (a prolonged and painful erection lasting more than 4 hours)
- Sudden hearing loss
- Sudden vision loss (NAION)
- Hypotension (low blood pressure)
- Syncope (fainting)
Drug interaction
Sildenafil is primarily metabolized by the CYP3A4 and CYP2C9 hepatic enzyme pathways. Concomitant use with inhibitors or inducers of these enzymes can affect plasma concentrations.
- Absolute Contraindication: Organic nitrates and nitric oxide donors.
- Potent CYP3A4 Inhibitors: Concomitant use with potent inhibitors like ritonavir, indinavir, ketoconazole, itraconazole, and clarithromycin significantly increases sildenafil exposure. A maximum dose of 25 mg within a 48-hour period is recommended.
- Alpha-blockers: Concomitant use can potentiate the blood-pressure-lowering effects. Dose adjustment and stable hemodynamic status are required.
- Other Antihypertensives: Additive hypotensive effects are possible.
- Alcohol: Excessive consumption can increase the risk of orthostatic hypotension and dizziness.
Missed dose
Viagra Sublingual is not intended for scheduled daily use. It is taken on an as-needed basis. Therefore, the concept of a “missed dose” does not apply. Do not take an extra dose to make up for a missed one. Adhere to the maximum dosing frequency of once per day.
Overdose
In cases of overdose, the expected effects would be an exaggeration of the known dose-dependent adverse effects, including severe hypotension, syncope, and prolonged erection.
Management:
- Standard supportive measures should be applied.
- For severe hypotension, active cardiovascular support may be required, including fluid administration. Note that organic nitrates are contraindicated.
- For priapism (erection lasting >4 hours), immediate medical attention is urgent to avoid long-term penile tissue damage and permanent impotence. Treatment may involve aspiration of blood or injection of alpha-adrenergic agonists into the corpus cavernosum.
Storage
- Store in the original blister pack or pouch at room temperature (15°C - 30°C or 59°F - 86°F).
- Protect from light and moisture.
- Keep out of reach of children and pets.
- Do not use after the expiration date printed on the packaging.
Disclaimer
This product information is intended for educational and informational purposes only and does not constitute medical advice. It is not a substitute for a consultation with a qualified healthcare professional. Always read the medication guide provided with your prescription. Do not initiate or alter any course of treatment without first consulting a physician who is aware of your complete medical history and current medication list. The information provided here is based on the typical profile of sildenafil sublingual formulations and may not be exhaustive.
Reviews
Clinical and patient-reported outcomes consistently demonstrate the efficacy of sildenafil for the treatment of erectile dysfunction. The sublingual formulation offers a valuable alternative for patients seeking a faster onset of action or those with difficulties swallowing conventional tablets. In clinical practice, the reported onset is frequently noted to be within 15-20 minutes, which patients often cite as a significant benefit over the standard oral formulation. Adherence to prescribing guidelines regarding contraindications, particularly the avoidance of nitrates, is paramount for patient safety.