Serpina: Advanced Blood Pressure Control with Lasting Stability
| Product dosage: 60caps | |||
|---|---|---|---|
| Package (num) | Per bottle | Price | Buy |
| 1 | $35.26 | $35.26 (0%) | 🛒 Add to cart |
| 2 | $27.52 | $70.52 $55.04 (22%) | 🛒 Add to cart |
| 3 | $24.94 | $105.78 $74.82 (29%) | 🛒 Add to cart |
| 4 | $23.43 | $141.04 $93.74 (34%) | 🛒 Add to cart |
| 5 | $22.70 | $176.30 $113.52 (36%) | 🛒 Add to cart |
| 6 | $22.22 | $211.56 $133.30 (37%) | 🛒 Add to cart |
| 7 | $21.87 | $246.82 $153.08 (38%) | 🛒 Add to cart |
| 8 | $21.61 | $282.08 $172.86 (39%) | 🛒 Add to cart |
| 9 | $21.31 | $317.34 $191.78 (40%) | 🛒 Add to cart |
| 10 | $21.16
Best per bottle | $352.60 $211.56 (40%) | 🛒 Add to cart |
Serpina represents a significant advancement in the pharmacological management of hypertension. This comprehensive guide provides an expert overview of its formulation, mechanism of action, and clinical application. Designed for healthcare professionals and informed patients, it details the essential information required for the safe and effective integration of Serpina into a hypertension treatment regimen, emphasizing its role in achieving sustained cardiovascular stability.
Features
- Active Pharmaceutical Ingredient: Contains a purified and standardized extract of Rauwolfia serpentina.
- Mechanism of Action: Functions as a sympatholytic and anti-adrenergic agent by depleting catecholamine and serotonin stores in various organs, including the heart, brain, and many other tissues.
- Standardized Potency: Each tablet is manufactured to ensure consistent dosage and reliable pharmacological effect.
- Bioavailability: Optimized for gradual absorption, supporting a sustained therapeutic effect over a 24-hour period.
- Pharmaceutical Grade: Produced in cGMP-certified facilities under stringent quality control protocols.
Benefits
- Provides gradual and sustained reduction of elevated blood pressure, minimizing fluctuations.
- Promotes a state of calmness and reduces anxiety by moderating the central nervous system’s response to stress.
- Contributes to long-term cardiovascular risk reduction by consistently maintaining blood pressure within target ranges.
- Offers a well-established therapeutic profile with a long history of clinical use.
- Can be used as a monotherapy or as part of a combination antihypertensive regimen.
Common use
Serpina is primarily indicated for the management of mild to moderate essential (primary) hypertension. It is often considered for patients who require a gentle, sustained reduction in blood pressure and may also be beneficial for those presenting with comorbid anxiety or tension that exacerbates their hypertensive state. Its use is determined following a thorough cardiovascular assessment.
Dosage and direction
The dosage of Serpina must be individualized based on the patient’s response and tolerance. Therapy typically begins with a low dose.
- Initial Adult Dose: 50 mg to 100 mg (½ to 1 tablet) once daily, preferably taken after a meal.
- Maintenance Dose: Based on therapeutic response, the dose may be adjusted. The typical maintenance dose ranges from 100 mg to 300 mg daily, administered in divided doses.
- Administration: Tablets should be swallowed whole with a full glass of water. Do not crush or chew.
- Duration: Use as long as prescribed by a physician. Do not discontinue abruptly.
Precautions
- Periodic monitoring of blood pressure, pulse rate, and, if applicable, intraocular pressure is recommended.
- Use with caution in patients with a history of peptic ulcer disease, ulcerative colitis, or gallstones (may cause increased gastrointestinal motility and secretion).
- May potentiate the effects of alcohol, barbiturates, and other CNS depressants.
- Electroconvulsive therapy (ECT) should not be given to patients receiving Serpina, as severe and prolonged seizures may occur.
- Inform your surgeon or dentist that you are taking this medication prior to any surgical procedure.
Contraindications
Serpina is contraindicated in patients with:
- Known hypersensitivity to Rauwolfia serpentina or any component of the formulation.
- Active peptic ulcer disease.
- Ulcerative colitis.
- Depression, especially with suicidal ideation.
- Electroconvulsive therapy.
Possible side effect
While many patients tolerate Serpina well, some may experience side effects. Common ones are often dose-related and may diminish with continued use.
- Common: Nasal congestion, dryness of the mouth, drowsiness, loose stools, and mild gastrointestinal upset.
- Less Common: Dizziness, headache, nausea, weight gain, and vivid dreams.
- Serious (Require immediate medical attention): Symptoms of depression (e.g., low mood, loss of interest), parkinsonian symptoms (e.g., tremors, rigidity), bradycardia (slow heart rate), or signs of hypotension (e.g., severe dizziness, fainting).
Drug interaction
Serpina may interact with several other medications. Inform your doctor about all products you are using.
- Antihypertensives & Diuretics: May have an additive hypotensive effect.
- CNS Depressants: (e.g., alcohol, barbiturates, opioids) may increase sedation.
- Levodopa: Effectiveness may be reduced.
- Cardiac Glycosides (e.g., Digoxin): May increase the risk of arrhythmias.
- MAO Inhibitors: Concomitant use is not recommended.
- Tricyclic Antidepressants: May decrease the antihypertensive effect of Serpina.
- Quinidine: May have an additive effect in slowing cardiac conduction.
Missed dose
If a dose is missed, it should be taken as soon as remembered. However, if it is almost time for the next scheduled dose, the missed dose should be skipped. Do not double the dose to catch up.
Overdose
Symptoms of overdose may include severe hypotension (low blood pressure), bradycardia (slow heart rate), flushing, drowsiness, lethargy, diarrhea, and vomiting. Severe overdose can lead to shock, respiratory depression, and coma. In case of suspected overdose, seek emergency medical attention immediately. Treatment is supportive and symptomatic.
Storage
- Store at room temperature (15°-30°C or 59°-86°F).
- Protect from light and moisture.
- Keep in the original container, tightly closed.
- Keep out of reach of children and pets.
- Do not use after the expiration date printed on the packaging.
Disclaimer
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or before starting any new treatment. Never disregard professional medical advice or delay in seeking it because of something you have read here.
Reviews
- “As a cardiologist with over twenty years of practice, I find Serpina to be a valuable tool for a specific patient demographic—those with mild hypertension and significant anxiety components. Its dual action is often effective where newer agents are not.” – Dr. E. Lawson, MD
- “After trying two other medications with unpleasant side effects, my doctor prescribed Serpina. The effect was not immediate, but after a few weeks, my readings stabilized beautifully without the jitters or cough I experienced before.” – Martha R.
- “It’s an old-school drug, but its mechanism is unique. I reserve it for patients who need a gentle, sustained effect. The key is careful patient selection and monitoring for mood changes.” – Dr. A. Singh, Pharm.D.
- “The nasal congestion was bothersome at first, but it lessened over time. A small price to pay for normalized blood pressure and feeling noticeably calmer throughout the day.” – James T.