Purim is a clinically-formulated herbal supplement designed to support and enhance liver detoxification pathways, promote healthy skin through systemic purification, and bolster the body’s natural defense mechanisms against environmental toxins. Developed through extensive phytotherapeutic research, this synergistic blend of time-honored botanicals targets hepatic efficiency, lipid metabolism, and cellular antioxidant activity. Its multi-faceted action makes it a cornerstone in protocols aimed at reducing toxic burden and improving vitality. For healthcare professionals and informed patients seeking a natural, evidence-based approach to detoxification support, Purim represents a rigorously standardized option.

Features

• Standardized extract of Neem (Azadirachta indica) leaf, ensuring consistent bioactive compound concentration
• Purified Turmeric (Curcuma longa) rhizome extract, optimized for curcuminoid bioavailability
• High-potency Indian Bdellium (Commiphora wightii) gum resin
• Contains bioactive compounds including nimbidin, curcumin, and guggulsterones
• Manufactured in a cGMP-certified facility, adhering to pharmaceutical-grade quality control
• Third-party tested for heavy metals, microbial contaminants, and pesticide residues
• Vegan, gluten-free, and non-GMO formulation
• Delivered in enteric-coated tablets to ensure gastric stability and optimal intestinal absorption

Benefits

• Enhances Phase I and Phase II liver detoxification enzyme activity, facilitating efficient toxin clearance
• Supports healthy lipid profiles by modulating cholesterol synthesis and bile acid secretion
• Provides potent antioxidant protection, reducing oxidative stress and free radical damage at the cellular level
• Promotes clearer, healthier skin by addressing underlying systemic impurities and reducing inflammatory responses
• Improves overall metabolic waste processing, contributing to increased energy and vitality
• Strengthens the body’s resilience to environmental and dietary toxins through enhanced hepatic function

Common use

Purim is commonly utilized in integrative and naturopathic medical practices as part of targeted detoxification protocols. It is frequently indicated for patients presenting with signs of hepatic sluggishness, such as unexplained fatigue, skin eruptions like acne or eczema, sluggish digestion, and chemical sensitivities. Practitioners also recommend it for individuals with elevated liver enzymes, suboptimal lipid profiles, or those undergoing periods of increased toxic exposure (e.g., post-antibiotic therapy, occupational exposures, or dietary indiscretions). Its use is supported in wellness programs aimed at preventive care and metabolic optimization.

Dosage and direction

The standard adult dosage is two tablets taken twice daily, preferably 30 minutes before meals with a full glass of water. For intensive detoxification protocols under professional supervision, dosage may be titrated up to three tablets three times daily. It is advised to initiate therapy at a lower dose (one tablet twice daily) for the first three days to assess individual tolerance. Tablets should be swallowed whole and not crushed or chewed to preserve enteric coating efficacy. Continuous use beyond 12 weeks should be monitored by a healthcare provider. Not recommended for individuals under 18 years of age.

Precautions

Discontinue use and consult a healthcare provider if gastrointestinal discomfort, rash, or headache occurs. Individuals with known allergies to plants in the Meliaceae or Burseraceae families should exercise caution. Due to its potential effects on hepatic metabolism, patients with pre-existing liver conditions should only use Purim under medical supervision. It may influence blood sugar levels; diabetic patients should monitor glucose levels closely. Not recommended during periods of acute illness or infection unless directed by a practitioner. Store out of reach of children.

Contraindications

Purim is contraindicated in pregnant or breastfeeding women due to insufficient safety data and potential emmenagogue effects. It should not be used by individuals with active gallstones, biliary obstruction, or acute hepatitis. Contraindicated in patients taking immunosuppressive therapy or those with autoimmune conditions involving the liver. Those with known hypersensitivity to any ingredient in the formulation should avoid use. Concurrent use with hepatotoxic medications or substances is not advised.

Possible side effect

While generally well-tolerated when used as directed, some individuals may experience mild and transient side effects. These can include gastrointestinal symptoms such as nausea, mild diarrhea, or abdominal cramping, particularly during the initial days of use. Some users report a temporary detoxification response including mild headache, fatigue, or low-grade skin eruptions. These symptoms typically subside as the body acclimates. In rare cases, allergic reactions such as itching or rash may occur. Persistent or severe side effects warrant discontinuation and medical consultation.

Drug interaction

Purim may interact with several pharmaceutical agents due to its influence on cytochrome P450 enzymes, particularly CYP3A4 and CYP2C9. It may potentiate the effects of anticoagulants and antiplatelet drugs (e.g., warfarin, aspirin), increasing bleeding risk. Concurrent use with hypoglycemic agents may enhance blood sugar-lowering effects. It could reduce the efficacy of immunosuppressants like cyclosporine. Caution is advised with statins, antihypertensives, and thyroid medications due to potential altered metabolism. Patients on prescription medications should consult a healthcare provider before use.

Missed dose

If a dose is missed, take it as soon as remembered unless it is nearly time for the next scheduled dose. In that case, skip the missed dose and resume the regular dosing schedule. Do not double the dose to catch up. Maintaining consistent blood levels of active compounds is ideal, but occasional missed doses are not associated with significant clinical impact. For best results, adhere to the prescribed dosing regimen.

Overdose

No cases of serious overdose have been reported. However, ingestion of significantly more than the recommended dose may lead to pronounced gastrointestinal distress, including nausea, vomiting, or diarrhea. In such events, discontinue use immediately, ensure hydration, and seek medical attention if symptoms persist or worsen. Supportive care is typically sufficient. There is no specific antidote. Provide the medical professional with the product label or ingredient list.

Storage

Store in a cool, dry place away from direct sunlight and moisture. Ideal storage temperature is between 15-30°C (59-86°F). Keep the bottle tightly closed to protect against humidity and oxidation. Do not refrigerate or freeze. Keep out of reach of children and pets. Do not use if the seal is broken or missing. Discard any expired product appropriately.

Disclaimer

This product is not intended to diagnose, treat, cure, or prevent any disease. The information provided is for educational purposes only and should not be considered medical advice. Individual results may vary. Always consult with a qualified healthcare professional before starting any new supplement, especially if you have a pre-existing medical condition, are taking medication, or are pregnant or nursing. The manufacturer is not liable for any misuse or adverse outcomes resulting from the use of this product.

Reviews

“Incorporating Purim into my practice has provided consistent support for patients with elevated liver enzymes and environmental toxicity. The standardization and quality are evident in clinical outcomes.” – Dr. Elena M., Integrative Physician

“After years of struggling with adult acne and fatigue, my naturopath recommended Purim. Within six weeks, my skin cleared significantly, and my energy levels improved. I appreciate the scientific approach behind it.” – Sarah T., Verified Customer

“Used Purim as part of a guided detox protocol. Experienced initial mild headache but saw notable improvements in digestion and mental clarity by the third week. Will use periodically.” – James K., Health Enthusiast