Modvigil: Enhance Wakefulness and Cognitive Performance
| Product dosage: 200 mg | |||
|---|---|---|---|
| Package (num) | Per pill | Price | Buy |
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| 200 | $0.81 | $349.73 $162.54 (54%) | 🛒 Add to cart |
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| 500 | $0.65
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Modvigil is a high-quality generic pharmaceutical formulation of modafinil, designed to promote wakefulness and support cognitive function in individuals with excessive sleepiness. As a central nervous system stimulant, it is widely recognized for its efficacy in managing sleep disorders such as narcolepsy, shift work sleep disorder, and obstructive sleep apnea. Manufactured to stringent standards, Modvigil offers a reliable and accessible option for patients and healthcare providers seeking an evidence-based approach to improving alertness and mental acuity. Its well-characterized pharmacokinetic profile and favorable safety record make it a cornerstone therapy in sleep medicine and neuroenhancement.
Features
- Contains 200 mg modafinil per tablet
- Film-coated for ease of swallowing
- Manufactured in GMP-certified facilities
- Long half-life (~15 hours) for sustained effect
- Minimal cytochrome P450 enzyme induction
- Bioequivalent to brand-name modafinil
Benefits
- Promotes prolonged wakefulness without jitteriness or euphoria
- Enhances cognitive functions including memory, attention, and executive function
- Improves quality of life for individuals with sleep disorders
- Supports shift workers in maintaining alertness during non-standard hours
- Reduces excessive daytime sleepiness with once-daily dosing
- Low potential for abuse compared to traditional stimulants
Common use
Modvigil is primarily indicated for the treatment of excessive sleepiness associated with narcolepsy, obstructive sleep apnea (as adjunct to primary airway therapy), and shift work sleep disorder. Off-label, it is sometimes used to address fatigue in conditions such as multiple sclerosis, depression, and Parkinson’s disease, though such use should be carefully supervised by a healthcare professional. It is also utilized in certain contexts for cognitive enhancement, though this application remains outside approved labeling and should be approached with caution and medical guidance.
Dosage and direction
The standard recommended dose of Modvigil is 200 mg taken orally once daily, preferably in the morning. For shift work sleep disorder, it should be taken approximately one hour before the start of the work shift. Dosage may be adjusted based on individual response and tolerability, though doses above 400 mg per day are not recommended. Tablets should be swallowed whole with water and may be taken with or without food, though consistent administration with food may reduce potential gastrointestinal discomfort.
Precautions
Patients should be advised that Modvigil may impair the ability to engage in potentially hazardous activities, such as operating machinery or driving. Caution is advised in those with a history of psychosis, depression, mania, or cardiovascular disease. Regular monitoring of blood pressure and heart rate is recommended during treatment. Use during pregnancy or breastfeeding should only be considered if the potential benefit justifies the potential risk to the fetus or infant. Patients with severe hepatic impairment should receive a reduced dose.
Contraindications
Modvigil is contraindicated in patients with known hypersensitivity to modafinil or armodafinil, or any component of the formulation. It should not be used in those with symptomatic ischemic heart disease, left ventricular hypertrophy, or mitral valve prolapse associated with central nervous system stimulant use. Concomitant use with monoamine oxidase inhibitors (MAOIs) is contraindicated due to the risk of hypertensive crisis.
Possible side effects
Common side effects may include headache, nausea, nervousness, anxiety, insomnia, dizziness, and dry mouth. Less frequently, patients may experience palpitations, tachycardia, hypertension, diarrhea, or blurred vision. Serious but rare adverse effects include Stevens-Johnson syndrome, angioedema, multiorgan hypersensitivity reactions, and psychiatric symptoms such as aggression or hallucinations. Any severe or persistent side effects should be reported to a healthcare provider immediately.
Drug interaction
Modvigil is a weak inducer of CYP3A4/5 and may reduce the plasma concentrations of drugs metabolized by these enzymes, such as cyclosporine, ethinyl estradiol, midazolam, and triazolam. Conversely, drugs that inhibit CYP2C19 (e.g., fluoxetine, omeprazole) may increase modafinil levels. Concurrent use with other CNS stimulants may exacerbate sympathetic effects. Caution is advised when co-administering with warfarin, theophylline, clozapine, or hormonal contraceptives.
Missed dose
If a dose is missed, it should be taken as soon as possible on the same day. However, if it is near bedtime or the next dose is due, the missed dose should be skipped to avoid insomnia. Doubling the dose is not recommended.
Overdose
Symptoms of overdose may include agitation, insomnia, tachycardia, hypertension, anxiety, confusion, nausea, or tremor. In severe cases, hallucinations, arrhythmias, or hyperpyrexia may occur. Management is supportive and may include activated charcoal, symptomatic treatment, and cardiovascular monitoring. There is no specific antidote.
Storage
Store at room temperature (15–30°C or 59–86°F) in a dry place, protected from light and moisture. Keep out of reach of children and pets. Do not use after the expiration date printed on the packaging.
Disclaimer
This information is intended for educational purposes only and does not constitute medical advice. Modvigil is a prescription medication and should only be used under the supervision of a qualified healthcare professional. Always follow your physician’s instructions and read the patient information leaflet provided with the medication. Do not self-diagnose or self-prescribe.
Reviews
Clinical studies and patient reports generally reflect positive experiences with Modvigil, particularly regarding its efficacy in reducing daytime sleepiness and improving cognitive function. Many users note improved productivity and alertness with minimal side effects when used as directed. However, individual responses may vary, and some report headaches or sleep disturbances. Long-term user satisfaction often depends on appropriate medical supervision and adherence to prescribed dosing.