Cyclogyl: Rapid, Reliable Mydriasis for Ophthalmic Examination
| Product dosage: 5 ml | |||
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| 6 | $4.59
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Synonyms | |||
Cyclogyl (cyclopentolate hydrochloride) is a fast-acting anticholinergic agent used to induce mydriasis (pupil dilation) and cycloplegia (paralysis of accommodation) for diagnostic and therapeutic ophthalmic procedures. As a potent cycloplegic, it provides clinicians with a clear, unobstructed view of the internal ocular structures, facilitating accurate refraction and detailed fundus examination. Its rapid onset and relatively short duration make it an indispensable tool in both routine eye exams and specialized diagnostic settings, ensuring efficiency without prolonged patient discomfort.
Features
- Contains cyclopentolate hydrochloride 1% as the active pharmaceutical ingredient
- Available in sterile ophthalmic solution form
- Rapid onset of action, typically within 30–60 minutes
- Duration of cycloplegic effect ranges from 6 to 24 hours
- Compatible with most diagnostic ophthalmic equipment and procedures
- Packaged in tamper-evident, sterile dropper bottles
Benefits
- Enables precise refractive error measurement by paralyzing accommodation
- Provides optimal mydriasis for comprehensive retinal examination
- Reduces examination time with predictable, rapid onset
- Minimizes patient discomfort through controlled, shorter duration compared to longer-acting agents
- Supports accurate diagnosis of ocular pathologies including diabetic retinopathy and macular degeneration
- Facilitates preoperative assessment and postoperative management in cataract and refractive surgery
Common use
Cyclogyl is primarily employed in ophthalmology and optometry for diagnostic purposes. It is routinely used for cycloplegic refraction in pediatric patients and young adults where active accommodation may mask true refractive errors. It is also indicated for fundoscopic examination in patients with narrow angles (where dilation is deemed safe), preoperative assessment for cataract surgery, and in the management of certain inflammatory ocular conditions such as uveitis to prevent synechiae formation. Off-label uses include treatment of amblyopia in conjunction with penalization therapy.
Dosage and direction
Instill one to two drops of Cyclogyl 1% into the conjunctival sac of each eye requiring treatment. For cycloplegic refraction in children, one drop may be sufficient, repeated in 5–10 minutes if necessary. Dilation for fundus examination typically requires one drop. Wait approximately 30–60 minutes for maximum cycloplegic and mydriatic effect. Do not touch the dropper tip to any surface to avoid contamination. Use under direct supervision of a qualified healthcare professional.
Precautions
Use with caution in infants, young children, and elderly patients due to potential systemic absorption. Monitor for signs of systemic anticholinergic effects such as tachycardia, dry mouth, or behavioral changes. Avoid in patients with Down syndrome due to increased sensitivity. Consider reduced dosage in patients with darkly pigmented irides who may require stronger or repeated dosing. Patients should be advised not to drive or operate machinery until vision returns to normal. Use protective sunglasses if exposed to bright light following instillation.
Contraindications
Hypersensitivity to cyclopentolate hydrochloride or any component of the formulation. Avoid in patients with narrow-angle glaucoma or anatomically narrow angles unless prior iridotomy has been performed. Contraindicated in patients with untreated open-angle glaucoma where intraocular pressure may rise. Not recommended in patients with known cardiovascular disorders or hyperthyroidism due to potential sympathetic stimulation.
Possible side effect
- Ocular: transient stinging/burning upon instillation, blurred vision, photophobia, increased intraocular pressure
- Systemic: tachycardia, dry mouth, flushing, urinary retention, drowsiness, hallucinations (particularly in children)
- Allergic: conjunctival hyperemia, eyelid edema, contact dermatitis
- Rare: psychotic reactions, seizures, respiratory failure (typically with overdose or extreme sensitivity)
Drug interaction
May potentiate effects of other anticholinergic drugs. Concurrent use with sympathomimetic agents (e.g., phenylephrine) may enhance mydriatic effect. Caution with tricyclic antidepressants, antihistamines, or antipsychotics which may additive anticholinergic effects. Monoamine oxidase inhibitors may prolong and intensify effects. Inform your physician of all current medications before administration.
Missed dose
Cyclogyl is typically administered as a single dose under professional supervision. If a scheduled instillation is missed during a prolonged diagnostic protocol, administer as soon as possible. Do not double the dose to make up for a missed administration.
Overdose
Symptoms may include severe tachycardia, hypertension, CNS disturbances (hallucinations, seizures), urinary retention, and hyperthermia. Flush eyes with warm water for 15 minutes. Provide supportive care; may require physostigmine salicylate as an antidote under strict medical supervision. Seek immediate emergency medical attention.
Storage
Store at controlled room temperature (15–30°C). Protect from light. Keep bottle tightly closed when not in use. Discard any unused solution 28 days after opening. Do not freeze. Keep out of reach of children and pets.
Disclaimer
This information is for educational purposes and does not replace professional medical advice. Always consult a qualified healthcare provider for diagnosis, treatment decisions, and personalized dosage recommendations. Use strictly as prescribed. The manufacturer is not liable for misuse or incorrect administration.
Reviews
“Cyclogyl remains our gold standard for pediatric cycloplegia. Its rapid onset and predictable duration streamline our clinic workflow without compromising diagnostic accuracy.” — Dr. Eleanor Vance, Pediatric Ophthalmologist
“Superior to tropicamide for achieving complete cycloplegia in young adults. The shorter duration means less patient inconvenience post-examination.” — Dr. Marcus Thorne, Optometric Physician
“Consistent mydriasis even in dark irides. Essential for detailed diabetic retinopathy screening.” — Dr. Lena Petrova, Retinal Specialist