Aleve: Effective 12-Hour Pain Relief with Naproxen Sodium
| Product dosage: 250mg | |||
|---|---|---|---|
| Package (num) | Per pill | Price | Buy |
| 60 | $0.82 | $49.02 (0%) | 🛒 Add to cart |
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| 360 | $0.66
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Aleve is a leading over-the-counter analgesic containing naproxen sodium, a nonsteroidal anti-inflammatory drug (NSAID) recognized for its potent and long-lasting pain-relieving properties. Clinically formulated to provide up to 12 hours of continuous relief with a single dose, it targets inflammation at the source, making it a preferred choice for managing a variety of musculoskeletal and inflammatory pain conditions. Its extended duration of action reduces dosing frequency, supporting consistent therapeutic levels and patient compliance.
Features
- Active ingredient: Naproxen sodium (220 mg per tablet/caplet)
- Drug class: Nonsteroidal anti-inflammatory drug (NSAID)
- Duration of action: Up to 12 hours of pain relief per dose
- Formulations: Tablets, caplets, liquid gels, and easy-open arthritis caplets
- Non-habit forming; does not contain opioids or sedatives
- Coated for easier swallowing (select formulations)
Benefits
- Provides all-day or all-night relief with just two doses in 24 hours
- Reduces inflammation, addressing the root cause of pain rather than merely masking symptoms
- Effective for a broad spectrum of pain types, including arthritis, backache, and menstrual cramps
- Allows for sustained mobility and improved daily functioning
- Trusted by healthcare professionals and used by millions of patients worldwide
- Available without a prescription for convenient access
Common use
Aleve is commonly used for the temporary relief of minor aches and pains associated with conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, tendinitis, bursitis, gout, menstrual cramps, headache, toothache, backache, and muscular aches. It is also used to reduce fever.
Dosage and direction
For adults and children 12 years and older:
- Take 1 tablet/caplet every 8 to 12 hours while symptoms persist.
- For the first dose, you may take 2 tablets/caplets within the first hour.
- Do not exceed 2 tablets/caplets in any 8- to 12-hour period.
- Do not exceed 3 tablets/caplets in 24 hours.
Swallow with a full glass of water. Do not crush, chew, or break the tablet/caplet. Take with food or milk if stomach upset occurs.
Precautions
- Do not use for more than 10 days for pain or 3 days for fever unless directed by a doctor.
- May cause an increased risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke, which can be fatal.
- Risk may increase with duration of use; patients with cardiovascular disease or risk factors may be at greater risk.
- May cause an increased risk of serious gastrointestinal adverse events including bleeding, ulceration, and perforation, which can be fatal.
- Not recommended during the late stages of pregnancy.
- Use with caution in patients with hypertension, heart failure, edema, or renal impairment.
Contraindications
Do not use if:
- You have had an allergic reaction (e.g., asthma, urticaria, cold symptoms) to aspirin, naproxen, or other NSAIDs.
- You are in the third trimester of pregnancy.
- You have recently undergone coronary artery bypass graft (CABG) surgery.
- You have a history of gastrointestinal bleeding or perforation with previous NSAID use.
Possible side effects
Common side effects may include:
- Nausea, heartburn, stomach pain, indigestion
- Dizziness, headache, drowsiness
- Mild swelling or fluid retention
Serious side effects (seek medical attention immediately):
- Signs of heart problems (chest pain, shortness of breath, weakness, slurred speech)
- Signs of stomach bleeding (black/tarry stools, vomit that looks like coffee grounds)
- Liver problems (nausea, fatigue, jaundice)
- Kidney problems (change in amount of urine, swollen ankles/feet)
- Severe skin reaction (fever, sore throat, burning eyes, skin pain, red/purple rash)
Drug interaction
Aleve may interact with:
- Other NSAIDs (e.g., aspirin, ibuprofen)
- Anticoagulants (e.g., warfarin)
- SSRIs or SNRIs (e.g., fluoxetine, venlafaxine)
- ACE inhibitors, angiotensin receptor blockers, diuretics
- Lithium, methotrexate, cyclosporine
- Corticosteroids (e.g., prednisone)
Consult your healthcare provider before use if you are taking any prescription or nonprescription medications.
Missed dose
Since Aleve is taken on an as-needed basis, you are not likely to be on a dosing schedule. If you are taking it regularly and miss a dose, take it as soon as you remember. Skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
Overdose
Symptoms of overdose may include:
- Drowsiness, heartburn, nausea, vomiting
- Severe stomach pain, bloody or black stools
- Shallow breathing, fainting, coma
Seek emergency medical attention or call a poison control center immediately.
Storage
Store at room temperature (20–25°C or 68–77°F) away from moisture, light, and heat. Do not store in the bathroom. Keep the bottle tightly closed. Keep out of reach of children and pets.
Disclaimer
This information is not intended as medical advice. Always read the label and follow directions. Do not use if printed seal under cap is broken or missing. Consult a healthcare professional before use if you have underlying medical conditions, are taking other medications, or are pregnant or breastfeeding.
Reviews
Aleve is consistently highly rated by consumers for its long-lasting effectiveness, especially among individuals with chronic pain conditions such as arthritis. Many users report significant improvement in mobility and quality of life. Clinical studies support its efficacy and safety profile when used as directed. Common feedback highlights the convenience of twice-daily dosing and reliable relief from inflammatory pain.

