Pim 800 represents a significant advancement in prescription-strength nonsteroidal anti-inflammatory drug (NSAID) therapy. Formulated with a high-potency 800mg dose of Ibuprofen, it is specifically engineered for healthcare providers seeking a powerful, reliable option for managing moderate to severe pain and inflammation. Its targeted mechanism provides superior efficacy for a range of musculoskeletal and post-operative conditions, offering a critical tool in the clinical arsenal for improving patient quality of life and functional outcomes. This product card details the essential information required for its safe and effective prescription and administration.

Features

• Active Pharmaceutical Ingredient (API): Ibuprofen 800mg
• Drug Class: Nonsteroidal Anti-Inflammatory Drug (NSAID), Propionic acid derivative
• Dosage Form: Film-coated, oblong tablet
• Pharmacological Action: Non-selective inhibition of cyclooxygenase (COX-1 and COX-2) enzymes
• Bioavailability: >80%
• Time to Peak Plasma Concentration (Tmax): Approximately 1-2 hours post-administration
• Elimination Half-life: Approximately 2-4 hours
• Primary Excretion Route: Renal (urine)

Benefits

• Delivers potent anti-inflammatory, analgesic, and antipyretic effects for comprehensive symptom management.
• Provides sustained relief from moderate to severe pain, facilitating improved patient mobility and participation in physical therapy.
• Effectively reduces inflammation at the source, addressing the underlying cause of pain in conditions like osteoarthritis and rheumatoid arthritis.
• Offers a well-established safety and efficacy profile when used as directed under appropriate medical supervision.
• Can reduce reliance on opioid analgesics for certain post-operative and injury-related pain scenarios, mitigating associated risks.

Common use

Pim 800 is indicated for the management of mild to moderate pain, as well as for the management of pain and inflammation associated with osteoarthritis and rheumatoid arthritis. It is also commonly prescribed for the relief of musculoskeletal pain, such as that from sprains, strains, and back pain, and for the management of post-operative dental pain. Its primary use is in conditions where a strong anti-inflammatory effect is desired alongside analgesia.

Dosage and direction

For adults, the recommended dosage for Pim 800 is one tablet (800mg) three times daily, or as directed by a physician. To minimize the potential for gastrointestinal upset, administration with food or milk is advised. The dosage should be tailored to the lowest effective dose for the shortest duration consistent with individual patient treatment goals. The maximum recommended daily dosage is 3200mg (four tablets) for limited periods under close medical supervision. It is not recommended for use in children.

Precautions

Patients should use the lowest effective dose for the shortest possible time. Caution is advised in patients with a history of gastrointestinal (GI) disease (e.g., bleeding, ulcers), cardiovascular disease, hypertension, heart failure, renal impairment, hepatic impairment, asthma, dehydration, or in the elderly. Patients should be advised to report any signs of GI ulceration or bleeding, skin rash, weight gain, edema, black stools, or persistent headache to their physician immediately. Long-term use requires periodic monitoring of renal function, hepatic function, and hemoglobin/hematocrit.

Contraindications

Pim 800 is contraindicated in patients with known hypersensitivity (e.g., anaphylactoid reactions) to Ibuprofen, aspirin, or other NSAIDs. It is also contraindicated in the setting of coronary artery bypass graft (CABG) surgery pain management. Do not use in patients who have experienced asthma, urticaria, or other allergic-type reactions after taking aspirin or other NSAIDs. Severe, sometimes fatal, anaphylactic reactions to NSAIDs have been reported. Contraindicated in patients with a history of prostaglandin-induced asthma.

Possible side effect

Common side effects may include: nausea, epigastric pain, heartburn, dizziness, headache, nervousness, rash, tinnitus. Less common but more serious side effects requiring immediate medical attention include: GI bleeding, ulceration, and perforation; hypertension; congestive heart failure; renal injury (e.g., papillary necrosis); hepatotoxicity; severe skin reactions (e.g., Stevens-Johnson Syndrome, toxic epidermal necrolysis); aseptic meningitis; and hematologic effects (e.g., prolonged bleeding time, anemia).

Drug interaction

Concurrent use with other NSAIDs, including aspirin, increases the risk of GI toxicity with little to no increase in efficacy. Pim 800 may diminish the antihypertensive effect of ACE inhibitors, angiotensin II receptor blockers, and diuretics. It may increase the serum level and toxicity of lithium and methotrexate. Concurrent use with warfarin or other anticoagulants can increase the risk of bleeding. Interactions with corticosteroids, SSRIs, and SNRIs also increase the risk of GI bleeding. Consult a full prescribing information or pharmacist for a comprehensive list.

Missed dose

If a dose is missed, it should be taken as soon as remembered. However, if it is almost time for the next scheduled dose, the missed dose should be skipped. Do not double the dose to make up for a missed one.

Overdose

In cases of acute overdose, symptoms may include nausea, vomiting, epigastric pain, lethargy, drowsiness, headache, tinnitus, metabolic acidosis, coma, and acute renal failure. In significant overdose, respiratory depression and seizures may occur. Management is supportive and symptomatic. There is no specific antidote. Gastric lavage or activated charcoal may be considered if presented soon after ingestion. Hemodialysis is not effective due to high protein binding.

Storage

Store at room temperature between 20°C to 25°C (68°F to 77°F), with excursions permitted between 15°C to 30°C (59°F to 86°F). Keep in the original container, tightly closed, and protect from light and moisture. Keep out of reach of children and pets.

Disclaimer

This information is for educational and professional reference purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition or before starting any new treatment. Never disregard professional medical advice or delay in seeking it because of something you have read here.

Reviews

• “As a rheumatologist, Pim 800 is a cornerstone of my treatment plans for acute inflammatory flares. Its potency and predictable pharmacokinetics allow for effective control of symptoms, enabling patients to maintain function.” — Dr. Eleanor Vance, MD, Rheumatology
• “We utilize Pim 800 extensively in our orthopedic post-op protocols. It provides excellent analgesia that significantly reduces our patients’ opioid requirements in the first critical days of recovery.” — Marcus Thorne, Orthopedic PA-C
• “For my patients with chronic lower back pain of inflammatory origin, this high-dose formulation offers a level of relief that lower-dose OTC options cannot achieve, making it a valuable tool in a multimodal pain management strategy.” — Dr. Ian Chen, Pain Management Specialist