Ciprodex Ophthalmic Solution is a prescription medication combining ciprofloxacin, a potent fluoroquinolone antibiotic, with dexamethasone, a powerful corticosteroid. This synergistic formulation is designed to treat bacterial eye infections while simultaneously managing inflammation, offering comprehensive therapeutic action. It is indicated for conditions such as bacterial conjunctivitis and corneal ulcers, providing both antimicrobial and anti-inflammatory benefits in a single, convenient solution. Trusted by ophthalmologists, it delivers targeted efficacy with a well-established safety profile for appropriate patient populations.

Features

• Contains 0.3% ciprofloxacin (antibiotic) and 0.1% dexamethasone (corticosteroid)
• Preservative-free formulation in sterile, single-dose containers
• Clear, isotonic solution with pH balanced for ocular comfort
• Available in 2.5 mL and 5 mL dropper bottles
• Storage at controlled room temperature (15–30°C)
• Manufactured under aseptic conditions

Benefits

• Rapid bacterial eradication due to broad-spectrum antibiotic coverage
• Effective reduction of inflammation, pain, and discomfort
• Prevents potential scarring and visual impairment from severe infections
• Convenient twice-daily dosing supports adherence
• Suitable for both anterior and external ocular infections
• Minimizes risk of secondary complications through anti-inflammatory action

Common use

Ciprodex Ophthalmic Solution is commonly prescribed for bacterial infections of the eye and surrounding tissues where inflammatory components are present. Typical indications include bacterial conjunctivitis, blepharitis, and keratitis. It is also used post-operatively in ocular surgery to prevent infection and control inflammation. Its dual mechanism makes it particularly valuable in cases where swelling, redness, and pain accompany confirmed or suspected bacterial involvement.

Dosage and direction

The typical dosage for adults and children aged 1 year and older is one to two drops instilled into the affected eye(s) every 6 to 12 hours, depending on severity. Treatment usually continues for 7 days, though duration may be adjusted based on clinical response. Wash hands before use. Avoid touching the dropper tip to any surface to prevent contamination. Tilt the head back, pull down the lower eyelid, and apply drops into the conjunctival sac. Close eyes gently for 1–2 minutes after administration.

Precautions

Do not wear contact lenses during treatment. Discontinue use and consult a healthcare provider if symptoms worsen or do not improve within a few days. Prolonged use may result in secondary fungal or non-susceptible bacterial infection. Use with caution in patients with a history of ocular herpes simplex. Monitor intraocular pressure with extended use. Not for injection or use in the ear unless specifically indicated.

Contraindications

Ciprodex is contraindicated in patients with known hypersensitivity to ciprofloxacin, other quinolones, dexamethasone, or any component of the formulation. It is also contraindicated in most viral diseases of the cornea and conjunctiva, including epithelial herpes simplex keratitis, vaccinia, and varicella. Avoid use in fungal or mycobacterial ocular infections.

Possible side effect

Common side effects may include transient ocular burning, stinging, or discomfort upon instillation; blurred vision; conjunctival hyperemia; and foreign body sensation. Less frequently, patients may experience corneal deposits, eyelid itching, swelling, or tearing. Rare but serious side effects include corneal perforation, superinfection, and elevated intraocular pressure. Allergic reactions are possible.

Drug interaction

No specific drug interactions have been formally established with topical ophthalmic use. However, patients using other ocular medications should administer them at least 5–10 minutes apart to avoid dilution or interaction. Systemic interactions are unlikely due to low systemic absorption, but caution is advised in patients on other corticosteroids or immunosuppressive agents.

Missed dose

If a dose is missed, administer it as soon as possible. If it is nearly time for the next dose, skip the missed dose and resume the regular schedule. Do not double the dose to make up for a missed one.

Overdose

Topical overdose is unlikely to cause systemic symptoms due to minimal absorption. If accidentally ingested, seek medical attention. Ocular overdose may result in increased irritation or redness; rinse the eye gently with sterile saline or water if discomfort occurs.

Storage

Store at room temperature between 15°C and 30°C (59°F–86°F). Do not freeze. Keep the bottle tightly closed and protected from light. Discard any unused solution 28 days after opening. Do not use if the solution is discolored or contains particles.

Disclaimer

This information is for educational purposes and does not replace professional medical advice. Always consult a qualified healthcare provider for diagnosis, treatment choices, and personalized recommendations. Use only as directed by a physician.

Reviews

Clinical studies and post-market surveillance indicate high efficacy and patient satisfaction with Ciprodex Ophthalmic Solution. In controlled trials, it demonstrated superior bacterial eradication and anti-inflammatory response compared to antibiotic-only treatments. Patients frequently report rapid symptom relief and tolerability. Ophthalmologists value its reliability in managing complex ocular infections with inflammatory components.