Assurans is a phosphodiesterase type 5 (PDE5) inhibitor medication specifically formulated to address erectile dysfunction (ED) by enhancing blood flow to the penile tissues. Its active ingredient, Sildenafil Citrate, works synergistically with sexual stimulation to facilitate a firm and sustainable erection, providing a clinically validated solution for men seeking to regain sexual vitality. This prescription medication represents a cornerstone in modern urological and andrological practice, offering a reliable mechanism of action with a well-established efficacy and safety profile developed through decades of rigorous clinical research and real-world application.

Features

• Active ingredient: Sildenafil Citrate
• Available in multiple dosages: 25mg, 50mg, and 100mg film-coated tablets
• Rapid onset of action, typically within 30–60 minutes
• Duration of efficacy lasting up to 4–6 hours
• High selectivity for phosphodiesterase type 5 (PDE5) enzymes
• Manufactured under strict Good Manufacturing Practice (GMP) standards

Benefits

• Achieves and maintains erections sufficient for satisfactory sexual activity
• Improves overall sexual confidence and reduces performance-related anxiety
• Enhances relationship satisfaction and intimacy for both partners
• Offers a predictable and reliable treatment option with a high success rate
• Provides flexibility in sexual spontaneity due to its on-demand dosing
• Supported by extensive long-term clinical data affirming its safety and tolerability

Common use

Assurans is primarily prescribed for the treatment of erectile dysfunction (ED) in adult men. Erectile dysfunction is characterized by the consistent or recurrent inability to attain and/or maintain a penile erection sufficient for satisfactory sexual performance. The medication is indicated for use in various etiologies of ED, including vasculogenic, neurogenic, and psychogenic origins, as well as cases of mixed etiology. It is important to note that Assurans is not indicated for use in women, children, or adolescents, and it does not offer protection against sexually transmitted infections. Its use should be integrated into a broader approach to men’s health, which may include addressing underlying cardiovascular risk factors, psychological counseling, and lifestyle modifications.

Dosage and direction

The recommended starting dose of Assurans is 50mg, taken approximately one hour before anticipated sexual activity. Based on efficacy and tolerability, the dose may be increased to a maximum of 100mg or decreased to 25mg. The medication should be administered orally with a glass of water and can be taken with or without food; however, a high-fat meal may delay the onset of action. Dosing should be limited to once per 24-hour period. For optimal results, sexual stimulation is required. Healthcare providers may adjust dosing based on individual patient factors, including age, renal or hepatic impairment, and concomitant medications. Patients with severe hepatic impairment or severe renal impairment (creatinine clearance <30 mL/min) should start with the 25mg dose.

Precautions

Prior to initiating treatment with Assurans, a thorough medical evaluation should be conducted to diagnose erectile dysfunction, determine potential underlying causes, and assess cardiovascular health. Patients with cardiovascular conditions such as heart failure, coronary artery disease, or uncontrolled hypertension may be at increased risk during sexual activity; therefore, a stress test may be warranted. Use with caution in patients with anatomical deformation of the penis (e.g., Peyronie’s disease), conditions predisposing to priapism (e.g., sickle cell anemia, leukemia), or bleeding disorders. Avoid excessive alcohol consumption, as it may increase the risk of orthostatic hypotension and diminish efficacy. This medication does not protect against sexually transmitted diseases; appropriate prophylactic measures should be used.

Contraindications

Assurans is contraindicated in patients who are using any form of organic nitrates or nitric oxide donors (e.g., nitroglycerin, isosorbide mononitrate or dinitrate), either regularly or intermittently, due to the risk of profound hypotension. It is also contraindicated in patients with a known hypersensitivity to Sildenafil Citrate or any excipients in the formulation. Concomitant use with guanylate cyclase stimulators, such as riociguat, is contraindicated due to the potential for symptomatic hypotension. The medication is not indicated for use in women or pediatric populations.

Possible side effects

The most commonly reported adverse reactions are headache, flushing, dyspepsia, nasal congestion, and dizziness. These are generally mild to moderate in severity and transient. Visual disturbances, including changes in color perception (e.g., cyanopsia), blurred vision, and increased sensitivity to light, have been reported and are related to the inhibition of PDE6 in the retina. Less frequently, myalgia, back pain, and rash may occur. Priapism (a prolonged and painful erection lasting more than 4 hours) is a rare but serious adverse event that requires immediate medical attention to avoid permanent tissue damage. Sudden decrease or loss of hearing, sometimes accompanied by tinnitus and dizziness, has been reported in temporal association with PDE5 inhibitor use. Although rare, cardiovascular events, including myocardial infarction and arrhythmia, have been reported in temporal association with sexual activity and PDE5 inhibitor use, particularly in patients with preexisting cardiovascular risk factors.

Drug interaction

Assurans is primarily metabolized by CYP3A4 and to a lesser extent by CYP2C9. Concomitant use with potent CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir, clarithromycin) may significantly increase Sildenafil plasma concentrations; a dose reduction should be considered. Alpha-blockers (e.g., doxazosin, tamsulosin) may potentiate the blood-pressure-lowering effects; therefore, Assurans should be initiated at the 25mg dose if co-administered. Other antihypertensive agents may add to the hypotensive effects. Although interaction studies showed no effect on aspirin-induced bleeding time, caution is advised when administering with other anticoagulants or antiplatelet agents. Concomitant use with other PDE5 inhibitors is not recommended.

Missed dose

Assurans is prescribed for on-demand use prior to anticipated sexual activity; it is not intended for chronic daily dosing. Therefore, the concept of a “missed dose” does not apply. The medication should only be taken when needed, with a minimum interval of 24 hours between doses. Patients should not take an extra dose to make up for a missed opportunity.

Overdose

In cases of overdose exceeding the maximum recommended dose, the adverse event profile is expected to be consistent with the known side effects of Assurans, but with increased severity. Symptoms may include severe headache, profound hypotension, syncope, and prolonged erection. Standard supportive measures should be employed, including maintaining supine positioning to stabilize blood pressure. Hemodialysis is not expected to accelerate clearance, as Sildenafil is highly protein-bound and extensively metabolized. In the event of priapism, immediate urological consultation is necessary.

Storage

Store Assurans tablets at room temperature, between 15–30°C (59–86°F), in a dry place protected from light and moisture. Keep the medication in its original blister packaging until the moment of use to ensure stability and prevent degradation. Keep out of reach of children and pets. Do not use beyond the expiration date printed on the packaging.

Disclaimer

This information is intended for educational purposes only and does not constitute medical advice. Assurans is a prescription medication and should only be used under the supervision of a qualified healthcare professional. Always consult with your physician for a proper diagnosis and treatment plan tailored to your individual health status and needs. Do not initiate, discontinue, or change the dosage of any medication without professional guidance.

Reviews

“After struggling with ED for years, my urologist prescribed Assurans. The 50mg dose works consistently for me, with minimal side effects—just some mild flushing. It has genuinely restored my confidence and improved my relationship.” — Mark T., 54

“I was initially hesitant to try medication, but Assurans has been a game-changer. I take it about an hour before, and the effects are reliable. I appreciate that my doctor started me on a lower dose to assess tolerance.” — James L., 61

“Effective, but the headache was noticeable the first few times. It lessened with continued use. Important to remember it doesn’t work without stimulation.” — Robert K., 58

“As a healthcare provider, I value medications with a robust evidence base. I prescribe Assurans frequently due to its predictable pharmacokinetics and well-documented efficacy in a diverse patient population.” — Dr. Elena Rivers, Urologist

“I’ve been using Assurans for over a year now. It does what it’s supposed to do. Just be mindful of taking it on a full stomach—it can delay the effect.” — Daniel S., 49